Mezo Smoke Shop

Mezo Smoke Shop keeps its doors open 24/7, which is a big part of why folks in Tucson keep it on their radar. Stop in at two in the afternoon or two in the morning and someone is there to help. One late-night visitor remembered a helpful girl up front who took the time to make sure the bowl piece was the right one, then wrapped it carefully so it wouldn't break on the drive home. That kind of care is what regulars talk about.

The selection runs deep for a shop this size. You'll find vapes, e-liquid and vape juice, glass pipes and water pipes, tobacco pipes, cigarettes, hookah and shisha, and the everyday smoking accessories that people run out of at odd hours. Locals have long said the shelves are surprisingly well stocked and that the staff usually knows their stuff. Cheap cigarettes are a draw too, and the word around Tucson is the prices are generally fair.

There's even a food truck that sets up outside if you catch it at the right time. Being open 24 hours in this stretch of town means there's usually activity around, so it's smart to lock your car when you park. We'll be straight with you: a few people have grumbled that prices on the same item can shift from one visit to the next, so it's worth confirming what you're paying before you buy. Even so, plenty of Tucson smokers keep coming back, and this tobacco shop holds a solid, well-regarded reputation across the community.

If you need a smoke shop in Tucson that's actually open when everything else is closed, Mezo is one to keep in mind. Come by, tell them what you're after, and the staff will point you in the right direction.